BBSRC MRes/PhD Studentship Recruitment of Condensin to Replication Origins in Bacillus Subtilis



  • BBSRC Doctoral Training Partnership
  • Reference Code: CB093

Details:

Name of the supervisor(s)
Professor J Errington, Institute for Cell and Molecular Biosciences (ICaMB)

Dr LJ Wu, Institute for Cell and Molecular Biosciences (ICaMB)

Sponsor
This studentship is sponsored by BBSRC as part of the Doctoral Training Partnership (DTP).

Duration of the award
4 years (MRes Medical and Molecular Biosciences followed by a three-year PhD).

Project description
Spo0J (ParB) is a widely conserved chromosome segregation factor in bacteria.We recently showed that in Bacillus subtilis, Spo0J promotes chromosome segregation by recruiting another widely conserved protein complex, SMC (Condensin) to the origin of chromosome replication (oriC) region (Gruber and Errington, 2009, Cell 137, 685). The aim of the project is to investigate the molecular mechanisms underlying Spo0J and SMC function, thereby providing new insights into fundamental aspects of chromosome segregation.

Value of the Award and Eligibility
Depending on how you meet the BBSRC’s eligibility criteria, you may be entitled to a full or a partial award. A full award covers tuition fees at the UK/EU rate and an annual stipend of £13,590 (2012/13). A partial award covers fees at the UK/EU rate only.

Person Specification
Candidates should have or expect to achieve a first-class or upper-second-class Honours degree in a relevant science subject.

How to Apply
You must complete the University’s postgraduate application form. Select “Master of Research/Doctor of Philosophy (Medical Sciences) – Cell and Molecular Biosciences” as the programme of study. Only mandatory fields need to be completed (no personal statement required) but you must attach a copy of your CV and a covering letter, quoting the title of the studentship and reference number CB093.

Closing date for applications 
Prompt application is advised as this post is only available until a suitable candidate is appointed.

Further Information
For further details, please contact:
Professor Jeff Errington
E-mail: [email protected]
Telephone: +44 (0) 191 208 3232

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