Research Associates x3 (Fixed Term)



Salary: £27,854-£36,298 pa

Reference: RB00980

Closing date: 01 April 2013

Applications are invited for Postdoctoral Research positions focusing on the molecular pathogenesis of human myleoproliferative neoplasms and malignant haematopoiesis.  The posts form part of a research programme directed by Professor Tony Green in collaboration with Professor Bertie Gottgens (CIMR) and Dr Peter Campbell (Sanger Institute) (eg NEJM 356: 459, 2007; NEJM 359: 2778, 2008; Nature 461: 819, 2009; Cancer Cell 18: 524, 2010; NEJM 365: 1384, 2011; Developmental Cell 20: 597, 2011). 

The Green lab is based in the Cambridge Institute for Medical Research. Projects are available in several areas including:

1) Mutational landscape of myeloproliferative neoplasms, building on results of exome and genome sequencing – will require expertise in genome-scale approaches.

2) Transcriptional consequences of JAK2 mutations.  This will focus on STAT transcriptional programmes together with non-canonical JAK signalling and will entail ChIP-seq and other genome-scale approaches.

3) Molecular and cellular consequences of JAK2 mutations with a focus on signalling, DNA damage and DNA replication.

For more information on the groups see:

http://www.haem.cam.ac.uk/staff/senior-staff/professor-tony-green/

http://www.haem.cam.ac.uk/staff/senior-staff/professor-bertie-gottgens/

http://www.sanger.ac.uk/research/faculty/pcampbell/

Informal enquiries to Professor Tony Green (email: [email protected]).

Fixed-term: The funds for this post are available for 3 years in the first instance.

This appointment is subject to a health assessment. Whether an outcome is satisfactory will be determined by the University.

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Applications consisting of a full CV, letter of application and a signed CHRIS/6 application cover sheet (Parts 1 and 3 only) with the names and contact details of three referees should be sent to Mrs Christine Thouroude at [email protected] or by post to Mrs Thouroude, Cambridge Institute for Medical Research, Dept of Haematology, Wellcome Trust/MRC Building Box 139, Hills Road, Cambridge CB2 0XY.

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