Salary: Â£27,854-Â£36,298 pa
Closing date: 01 April 2013
Applications are invited for Postdoctoral Research positions focusing on the molecular pathogenesis of human myleoproliferative neoplasms and malignant haematopoiesis.Â The posts form part of a research programme directed by Professor Tony Green in collaboration with Professor Bertie Gottgens (CIMR) and Dr Peter Campbell (Sanger Institute) (eg NEJM 356: 459, 2007; NEJM 359: 2778, 2008; Nature 461: 819, 2009; Cancer Cell 18: 524, 2010; NEJM 365: 1384, 2011; Developmental Cell 20: 597, 2011).Â
The Green lab is based in the Cambridge Institute for Medical Research.Â Projects are available in several areas including:
1) Mutational landscape of myeloproliferative neoplasms, building on results of exome and genome sequencing – will require expertise in genome-scale approaches.
2) Transcriptional consequences of JAK2 mutations.Â This will focus on STAT transcriptional programmes together with non-canonical JAK signalling and will entail ChIP-seq and other genome-scale approaches.
3) Molecular and cellular consequences of JAK2 mutations with a focus on signalling, DNA damage and DNA replication.
For more information on the groups see:
Informal enquiries to Professor Tony Green (email: [email protected]).
Fixed-term: The funds for this post are available for 3 years in the first instance.
This appointment is subject to a health assessment. Whether an outcome is satisfactory will be determined by the University.
Applications consisting of a full CV, letter of application and a signed CHRIS/6 application cover sheet (Parts 1 and 3 only) with the names and contact details of three referees should be sent to Mrs Christine Thouroude at [email protected] or by post to Mrs Thouroude, Cambridge Institute for Medical Research, Dept of Haematology, Wellcome Trust/MRC Building Box 139, Hills Road, Cambridge CB2 0XY.