To celebrate the University’s research successes, the University of Hull is offering a PhD scholarship for candidates applying for the following project.
Closing Date: 14th August 2013
Start Date:Â 30 September 2013. Â
Informal enquiries:
Dr.C. Cawthorne               +44 (0)1482 466776       c.cawthorne@hull.ac.uk
Prof.J. Greenman            +44 (0)1482 465409 j.greenman@hull.ac.uk
How to apply
Visit our website via the âApplyâ button below.
Project outline
An exciting opportunity is available starting 30 September 2013, for a fully funded full time PhD studentship to develop novel imaging biomarkers for cancer.
Estrogen receptor-a is expressed in most breast cancers, and patients with ERa-positive (ERa+) tumours have longer overall survival and better response to hormone based therapies. The Progesterone Receptor (PR) is an estrogen-regulated gene, and there is evidence that PR expression in response to ER stimulation is predictive of response to anti-estrogenic therapies. Although ER and PR status are measured immunohistochemically in current clinical practice, molecular imaging of this pathway offers the ability to assess the whole disease burden in a patient longitudinally, allowing the assessment of heterogeneity and changes in response to therapy that may inform clinical management. The aim of this project is to screen a library of putative PR binding PET imaging agents for use as imaging biomarkers, using a wide range of in vitro and in vivo techniques. The project will make use of the recently installed Bioscan PET/CT scanner at the University of Hull, part of the new PET Research Centre.
Applicants should be highly motivated and have:
- A minimum Upper Second Class honours degree in a relevant subject from a recognised Institution
- Previous experience in the biological analysis of tissue will be an advantage
Further details
This full-time UK/EU PhD scholarship will include fees at the ‘home/EU’ student rate and maintenance of £13,726 (in 2013/14) for three years, depending on satisfactory progress.
PhD students at the University of Hull are required to follow modules for research and transferable skills development and gain a Masters level Certificate or Diploma in Research Training in addition to their research degree.