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Prolong Organ Survival After Transplantation (POSAT)

Reference Code: CL070

Closing Date: 21st December 2013

Details:

Name of the supervisors
Professor S Ali, Institute of Cellular Medicine

Professor J Kirby, Institute of Cellular Medicine

Sponsor
European Commission FP7, Marie Curie-Initial Training Networks (ITN), Innovative Doctoral Programmes (IDP).

Duration of the award
Three year Phd

Project description
The POSAT scheme will address this by training early stage researchers to function at this dynamic interface in order to address specific problems which contribute to chronic graft failure. This programme will meet two specific objectives: development of methods to reduce organ inflammation immediately after transplantation (thereby preserving long-term graft function), and identification of biomarkers which allow transplant patients to be stratified allowing individualized drug treatment. These complementary objectives will be addressed by allocation of a trainee-specific project to each of the 4 early stage researchers. Although based at Newcastle University, each trainee will spend significant periods working with carefully selected private sector partners and academics at another university in the NorthEast of England.

Project1: Analysis and manipulation of the time zero allograft transcriptome

Project 2: Analysis and Amelioration of Ischemia-Reperfusion Injury

Project 3: Identification of molecular biomarkers of fibrosis

Project4: Analysis of tissue re-modelling associated with allograft rejection

Further information can be found on the Institute of Cellular Medicine’s website.

Value of the award and eligibility
Two appointees will commence work in March, 2014 and a further two in October, 2014. For this reason, candidates with EU citizenship are eligible to apply for these posts if they have not been resident within the UK for more than 12 months within the three years prior to the project start dates.

Approximately £35,000 per year including living and mobility allowance. The salary is taxable at the UK rate. Appointees are not liable for payment of university tuition fees.

Person specification
Successful candidates will hold excellent first and masters level degrees in a relevant subject and will be fluent in English (minimum IELTS level 6).

Marie Curie funding is intended to promote the mobility of early stage researchers (no more than four years research experience after the end of a first degree) within the EU.

How to apply
Applicants should send a covering letter detailing their suitability for the fellowship, full C.V. and two academic references to Mrs Janice McIntyre (janice.mcintyre@ncl.ac.uk).

Further information
Informal enquiries to: 
Professors Simi Ali 
E-mail: Simi.Ali@newcastle.ac.uk
Or
John A Kirby
E-mail: john.Kirby@newcastle.ac.uk

For more information and to submit an application, please use the ‘Apply’ button below.